Researchers call for simplest-possible baselines in ML×Bio papers over flashy ablations

anshulkundaje · x · 2026-10-03

Yasa Baig argues ML×Bio papers favor cool architectural ablations while lacking basic controls: always baseline against the simplest possible models and explanations. Computational biologist Anshul Kundaje added that computational researchers need the same drilling, and that it matters even more for large models given their many moving parts and confounders.

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