MILK is faster but worse: synthetic data shows it underperforms even UMAP vs Bonsai

anshulkundaje · x · 2026-10-02

@NimwegenLab answers a common question: should you switch from Bonsai to the faster MILK for tree-based scRNA-seq visualization? No. On synthetic data MILK performs worse than even UMAP, showing that speed alone doesn't make methods interchangeable. #methodsmatter

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