SynthID Bio watermarks sequences and 3D structures, open for research use

GoogleDeepMind · x · 2026-10-01

DeepMind's blog details SynthID Bio: the approach adapts to data type, subtly guiding amino acid choices for sequences and adjusting atomic coordinates for predicted 3D structures to create a reliable detection signal. Experiments show watermarked designs (e.g., a VEGF-A protein binder) retain biological function. Motivation: novel AI designs can bypass traditional DNA synthesis screening, and mislabeled synthetic 3D structures risk polluting public databases. Tools are released openly for research use.

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