Blood Test Could Replace Tumor Biopsy for Personalized Neoantigen Vaccines, New Study Finds

EricTopol · x · 2026-09-29

Personalized neoantigen vaccines have already improved outcomes in refractory melanoma and shown promise in pilot studies of pancreatic cancer, glioblastoma, renal cell carcinoma and triple-negative breast cancer — but they required a tumor biopsy to identify antigens. A new study highlighted by Eric Topol shows the needed antigen information can now be obtained from a simple blood sample, potentially lowering the barrier for personalized cancer vaccines.

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