GRAIL Galleri trial of 142,000 fails to cut late-stage cancer incidence

EricTopol · x · 2026-09-25

Eric Topol highlights the GRAIL NHS Galleri randomized trial published in NEJM: with over 142,000 participants, the trial did not meet its primary endpoint — after three screening rounds of multicancer early-detection testing plus usual care, no lower incidence of stage III/IV cancers was observed across 12 prespecified cancers versus usual care alone.

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