FutureHouse Unveils 'Bio Millennium Problems': The Last Real Eval for AI in Biology

burny_tech · x · 2026-09-21

Edison Scientific and FutureHouse have assembled a set of Millennium Problems for Biology: chosen to be extremely hard to solve yet easy to validate in a simple lab environment. Solving any of them would mark a major advance in biotechnology, and most would materially contribute to curing disease. The authors call this, in a sense, the "last reasonable eval" for AI in biology. Primary work by @MichaelaThinks and @SGRodriques.

Quoting user @srikosuri added a half-joking wish list: mango-banana hybrids, plant-machine interfaces, solution-phase self-assembly of 3D memory chips, a brain the size of a building, browsing the web by thought via BMI, dinosaurs, and more.

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