Human brain organoids grow into working circuits inside mice, Stanford team reports in Nature
Dr_Singularity · x · 2026-09-18
- A Stanford team led by Sergiu P. Pașca (with Karl Deisseroth) published in Nature: human-derived brain organoids transplanted into mice grew to occupy much of the cortical space.
- The human cells developed diverse cell types, wired into the mouse nervous system, and formed organized neural circuits showing brain-like activity—the authors call this "developmental xenocortication."
- The model sidesteps the inaccessibility of human brain tissue, offering an in vivo platform for studying human brain development and disease; the paper is open access.
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