Genomics researcher defends AI variant prioritization paper: validation already sufficient
anshulkundaje · x · 2026-09-18
In an ongoing thread about a disease variant prioritization paper, genomics researcher Anshul Kundaje acknowledges that more experimental validation and direct testing is needed — but argues the paper's presented evaluation is more than sufficient to support its claims: that the score is likely a useful variant prioritization tool and the resource serves as a useful lookup table for anyone.
The exchange reflects a broader debate over how much experimental validation computational scoring tools require before publication.
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