What the New AVI Score Actually Is: A Genome-Wide Ranking, Not a Calibrated Pathogenicity Probability
anshulkundaje · x · 2026-09-18
AVI (AlphaGenome Variant Impact) is a genome-wide score for prioritizing potentially deleterious variants. Kundaje clarifies it is not a calibrated probability of pathogenicity and should not be read as one.
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