AVI Scores Each Variant Using 18 Features: AG, AlphaMissense, Conservation, LoF

anshulkundaje · x · 2026-09-18

AVI combines 10 AlphaGenome features with AlphaMissense scores (for coding variants), 2 conservation scores, 3 protein loss-of-function annotations, and indel indicators — 18 features per variant in total.

Related event: Stanford expert defends AlphaGenome variant scores in detailed thread, rebutting "AI slop" criticism(20 posts)→

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