AVI Score Offers Interpretable Functional Hypotheses for Variant Prioritization

anshulkundaje · x · 2026-09-18

Thread segment from Anshul Kundaje: the AVI score is reasonably interpretable and can generate functional hypotheses for why a variant is prioritized, which biologists or AI models can reason about — a useful handle for downstream mechanistic work.

Related event: Stanford expert defends AlphaGenome variant scores in detailed thread, rebutting "AI slop" criticism(20 posts)→

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