Interpretability Methods Run Directly on AlphaGenome to Pinpoint Disrupted Motifs

anshulkundaje · x · 2026-09-18

Thread segment from Anshul Kundaje: beyond the AVI score, interpretation methods can be applied directly on AlphaGenome to identify which sequence features (e.g. motifs) a variant disrupts, and for which readouts in which cell types — drilling from score to mechanism.

Related event: Stanford's Kundaje Reviews DeepMind's AVI Score: Competitive, Not Revolutionary, and Not "AI Slop"(35 posts)→

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