AVI Scores Are PHRED-Scaled and Traceable to Contributing Features
anshulkundaje · x · 2026-09-18
Thread segment from Anshul Kundaje: raw AVI scores from the trained classifier rank all 9 billion possible variants and are PHRED-scaled — AVI 10 = top 10%, 20 = top 1%, 30 = top 0.1%, 40 = top 0.01%. A cool feature: you can trace back through the model which features (binding, accessibility, splicing, expression) drive a high score.
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