Liquid AI's LFM longevity models hit Cell cover, beating GPT-5 and Gemini-3.1-Pro with 1.2B-2.6B params

helloiamleonie · x · 2026-09-17

Liquid AI, partnering with Insilico Medicine, published a Cell cover paper on foundation models for aging biology. They released LongevityBench, a 17-task eval suite spanning clinical records, DNA methylation, transcriptomics, plasma proteomics, and genetic evidence, plus two compact fine-tuned models — LFM2-1.2B-Longevity and LFM2-2.6B-Longevity — that set SOTA on biological longevity tasks, outperforming frontier models like Gemini-3.1-Pro, GPT-5, and Claude Opus. Models and benchmark are open on Hugging Face, showing domain-tuned small models rivaling much larger general ones.

Related event: Liquid AI and Insilico Medicine longevity research lands Cell cover, small models beat GPT-5(2 posts)→

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