Stanford team creates 'xenocortical mice' with ~92% human-derived cortex
MannyKayy · x · 2026-09-17
Sergiu Pasca's lab at Stanford, led by Konstantin Kaganovsky, published a Nature paper on "xenocortical mice" whose cortex is 92% occupied by a cortical organoid derived from human stem cells. The human cortical graft integrates deeply with the host nervous system, supporting organized neural activity and behavior — a new in vivo model for studying human cortex development and disease.
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