Fruit fly connectome's 166,700 neurons trained to play Overwatch at Masters level

benaratame · x · 2026-09-13

A developer trained the MaleCNS v1.0 fruit fly connectome — 166,700 neurons from the complete adult male fly brain map — using YOLOv5 and video pretraining data to play Overwatch in a keyboard environment with attention-based aiming, reaching Masters-level play, with best results on Mercy.

Context: Google Research and HHMI Janelia reconstructed the full adult male fruit fly brain and CNS connectome by combining millions of 2D images into 3D neural shapes, a major neuroscience milestone.

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