Fruit fly brain sim wired to a 1B LLM: 139,255 neurons now chat with you

TinfoilTricorn · x · 2026-09-12

A developer connected a full fruit fly brain connectome simulation to a 1B-parameter LLM: 139,255 neurons and 2.7 million synaptic connections.

Your message is converted into a sensory stimulus, the brain simulation runs, and the model reads the resulting neural activity to generate a reply — effectively letting you talk to a fruit fly's brain. A quirky but real crossover between connectome data and LLM generation pipelines, building on the recently released fly connectome.

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