Developer says OpenAI shut down his client's protein design project, vows open weights only

AIFlow_ML · x · 2026-09-10

A developer reports that OpenAI decided to fully shut down the protein design project he was building for a client, drawing the lesson that open-weight models are the only viable path forward. The incident highlights the fragility of businesses built on closed-model APIs, where unilateral vendor policy changes can kill downstream projects overnight.

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