Developer synthesizes PAC-3310, a ChatGPT-designed schizophrenia drug candidate, in his garage
CatAstro_Piyush · x · 2026-09-09
Developer Douglas Yao showed off a vial of PAC-3310, a novel compound designed with ChatGPT and synthesized in a garage chemistry lab he built.
- PAC-3310 is a selective M4 muscarinic receptor agonist targeting schizophrenia
- Modeled after the recent breakthrough drug Cobenfry (KarXT), but claimed to be improved
- A rare hands-on AI4Science case of an individual using AI for drug design; his follow-up posts are worth watching to verify the claims
Related event: Vibe Chemist Synthesizes Experimental Antipsychotic with ChatGPT in Garage(2 posts)→
More from Research
- The synthetic data bible: recommended starting point — yacinelearning · 2026-09-09
- Sam Altman: OpenAI will hunt for room-temperature superconductors with 1000s of AI agents — Dr_Singularity · 2026-09-09
- Nature: Connectomics Reveals How a Cerebellum-Like Circuit Learns Sensory Prediction — burny_tech · 2026-09-09
- 14B open model on one RTX 4090 matches hosted frontier model on text-to-SQL; mnemiq open-sourced — ycombinator · 2026-09-09
- Prof. Tom Yeh's new hand-solvable exercises demystify the context window — ProfTomYeh · 2026-09-09
- New discrete-diffusion LLM speedup paper Uno called out for similarity to Orthrus — _akhaliq · 2026-09-09