Microsoft's TALOS automates iterative genomic reanalysis for rare disease diagnosis
pswider · x · 2026-09-09
Microsoft Research published Talos, a system that scales rare disease diagnosis through automated, iterative genomic reanalysis: as new gene-disease evidence emerges, variants of unknown significance can be reclassified into a diagnosis.
The key design is a continuously running agent loop with an intact evidence trail throughout — which the poster argues is the real bar for clinical agents: not one-shot reasoning, but long-running, auditable updates.
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