Bio ML critique: many published models score within ~10% of a naive linear baseline
iskander · x · 2026-09-08
iskander (George Ho) observes that many published bio ML models score within roughly 10% of a naive linear baseline.
The short note points to a familiar pitfall in bio ML papers: models are benchmarked against deep learning baselines rather than simple linear regressions, making seemingly sophisticated models look better than they are.
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