Full Fruit Fly Connectome With 166,700 Neurons Runs Inside Minecraft

lfschiavo · x · 2026-09-06

Developer @menhguin has run the full retained MaleCNS v1.0 fruit fly connectome — all 166,700 neurons — inside Minecraft, with its simulated neural activity driving a fly's movement in-game. The project was built with help from OpenAI's GPT-6 Astra, with code and a mod coming soon; V1 is still in development.

Beyond being a gloriously absurd hack, it hints at a cheap, playful approach to connectome simulation and outreach.

Related event: Full Fruit-Fly Connectome Runs in Minecraft, Driving an In-Game Fly(9 posts)→

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