Clinic-in-the-Loop: why clinical trials are the real bottleneck breaking Eroom's Law

anshulkundaje · x · 2026-09-05

In an Asimov Press essay, Ruxandra Teslo examines why therapeutics has grown less productive despite stunning basic-science advances. Key points: Eroom's Law (drug development costs doubling every 9 years since the 1950s); her Clinical Trial Abundance Project arguing more, faster, more informative trials are the fix — co-authored with Jack Scannell; critics counter that easier trials treat biotech like a casino; and the view of Phase I oncology trials as iterative learning loops where knowledge comes from trying.

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