Deep Learning for RNA Design Makes Science Cover, AI Matches Expert Humans on Pseudoknots
rishabh16_ · x · 2026-09-04
Chaitanya Joshi announced that gRNAde, a deep learning system for RNA design that began as a side project during his CS PhD, has been published in Science and chosen as the cover article.
Key result: on the Eterna citizen-science platform, AI methods matched expert human players at inventing sequences that fold into RNA pseudoknots — complex structures where loops pair with distant parts of the same molecule.
This opens a route to automatically designing RNA therapeutics, sensors, and catalysts from scratch, capping a three-year journey from new ML modeling to experimental validation.
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