Claude Fable 5.1 Replicates and Extends Research; Mythos Writes Custom Kernels

BenBlaiszik · x · 2026-09-02

A user reported that Anthropic's Claude Fable 5.1 re-implemented an entire grad school paper, reproduced calculations, fixed approximations, derived a new analytical model, and solved a harder future work problem in just 7 hours. Additionally, the Mythos model wrote custom GPU kernels to speed up open-source comp bio models by 2.5x and cut GPU costs by 30-60%, with plans to open source these optimizations.

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