Promoter Atlas Designs Gene Therapy Control Layer via Computation
julia_kiseleva · x · 2026-09-01
Gene therapy requires precise control over gene expression—where, when, and how much—which starts with promoters. Julia Kiseleva introduced Promoter Atlas by Genomic Intelligence, a tool built to benchmark, compare, and design better promoters.
Core Functionality:
- Researchers specify where a therapeutic gene should be active, silent, and the desired expression range.
- The system evaluates natural and designed regulatory sequences, returning promoter candidates ready for synthesis and lab testing.
Vision & Context:
- Traditional development relies on cycles of biological trial and error.
- The future envisions therapeutic DNA designed computationally against biological specs, synthesized on demand, and validated experimentally.
- The lab's role shifts to validating top candidates rather than blind searching.
The project originated at the re:AGENT 2026 hackathon, testing if models could translate gene therapy requirements into ready-to-evaluate promoter sequences.
Related event: Genomic Intelligence Launches Promoter Atlas for Gene Therapy Design(2 posts)→
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