Anthropic's Fable Breaks RareBench Record After Relaxing Filters

danielmckinn0n · x · 2026-08-21

Anthropic's Fable model previously scored 0% on RareBench due to bio-related refusals. After relaxing filters, Fable took the lead with a staggering 41% + 7%, significantly beating @SpaceXAI @grok 4.6's previous record of 4.6%. The author plans to update the system to include Fable and rerun unsolved clinical genomes, expressing cautious optimism about diagnosing new cases.

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