Review of single-cell foundation models: 100+ models, perturbation prediction unsolved

david_van_dijk · x · 2026-08-20

A new review of the single-cell foundation model field covers 39 authors and 100+ models since 2021. Cell2Sentence, developed by the author's lab, is credited as the first model to teach an LLM to read a cell. The review notes that perturbation prediction remains an unsolved challenge, which is the focus of CellType Inc.

Related event: Survey Maps 100+ Single-Cell Foundation Models, Perturbation Prediction Unsolved(2 posts)→

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