Review reveals 100+ single-cell foundation models, perturbation prediction remains unsolved
david_van_dijk · x · 2026-08-20
- Context: A new review paper on the single-cell foundation model field has been released, featuring 39 authors.
- Status: Over 100 models have emerged in the field since 2021.
- Origins: The review traces Cell2Sentence and C2S-Scale from the author's lab as the origin of this approach.
- Challenge: The paper notes that "perturbation prediction" remains an unsolved problem, which is what CellType (@CellTypeinc) is currently building.
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