Claude achieves up to 35% success rate in protein binder design

anshulkundaje · x · 2026-08-19

Anthropic reports Claude's protein binder designs achieved binding success rates of 22%-35%, significantly outperforming the 10-15% field average. Responding to criticism that binder design isn't a proxy for drug discovery, Anthropic clarified it's a useful proxy, noting some designs bound several times more tightly than the best published de novo binders.

Related event: Anthropic Says Claude Designed Protein Binders for 14 of 15 Targets(45 posts)→

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