Predicting antibody distribution is far easier than designing localization, 99% of molecules never reach the target
anshulkundaje · x · 2026-08-18
Richard Fuisz argues that predicting where an antibody distributes in the body is far easier than designing a molecule to localize in a specific way. Truly disease-tissue-specific targets barely exist, and even when they do, 99% of molecules never reach the target site in the first place — highlighting the fundamental difficulty gap between distribution prediction and rational localization design.
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