A full workflow for fine-tuning AlphaGenome splicing heads on RNA-seq data
anshulkundaje · x · 2026-07-29
This is the full linked post for the same AlphaGenome fine-tuning write-up. It details a workflow for preprocessing, loading, debugging, and evaluating splicing-head training across RNA-seq modalities.
The case study uses SF3B1 K700E and wild-type samples to show how the model can be adapted to new transcriptomic inputs and evaluated on held-out genomic intervals.
Related event: Team Fine-Tunes AlphaGenome for RNA-seq Data Adaptation(4 posts)→
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