Nature Genetics review maps AI for regulatory genomics from OOD to interpretability
mo_lotfollahi · x · 2026-07-27
A Nature Genetics review on AI for regulatory genomics surveys the field from loss landscapes and out-of-distribution generalization to interpretability and ways to improve generalization with perturbation data.
The authors take an opinionated stance on where the field should go, highlighting active learning and continual learning as promising directions for fixing generalization issues in regulatory genomics models.
Related event: Nature Genetics Review Tackles AI Generalization in Regulatory Genomics(3 posts)→
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