MSA Pairformer Outperforms ESMC 6B in Protein Contact Prediction
sokrypton · x · 2026-07-22
Research shows that MSA Pairformer predicts protein contacts more accurately than ESMC 6B. Instead of simply scaling model size and training data following the bitter lesson, this approach leverages the rapidly growing scale of sequence data during inference.
More from Research
- NLI alone rejects 5/6 new agent memories; a 0.45 similarity gate fixes it all — Alternative_Pin9598 · 2026-10-26
- AI folks, stop saying "biology" when you mean drug development — KevinKaichuang · 2026-10-26
- ostris pre-training "Primal VAE": 1-channel latents match modern 8x VAEs via patching — ostrisai · 2026-10-26
- Shanghai AI Lab-led team releases 100-hour egocentric wearable dataset for humanoid training — ChuckDBrooks · 2026-10-26
- ConvFill: A 0.6B Talker Buys Time While a Large Reasoner Whispers the Real Answer — andimarafioti · 2026-10-26
- Flow Reasoning Models turn flow matching into iterative reasoners, hitting 99.5% on Sudoku-Extreme — alec_helbling · 2026-10-26