Profluent's 1.2B ProGen Model Generates De Novo Proteins Rivaling Natural Evolution

nathanbenaich · x · 2026-07-21

Profluent's first 1.2 billion parameter ProGen model—the largest in physical sciences at the time—successfully produced de novo proteins. These AI-generated proteins demonstrated incredibly high hit rates and functionality, rivaling natural proteins that have undergone millions of years of evolution.

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