AllTheBacteria standardizes 2.44M genomes for AI-driven biology
anshulkundaje · x · 2026-07-20
AllTheBacteria turns millions of microbial genomes into an AI-ready resource
The preprint introduces AllTheBacteria, an open, community-built platform that standardizes and makes searchable 2.44 million public bacterial and archaeal genomes.
To show what the resource enables, the team used it to find new peptide antibiotics. One candidate, ATB20, reduced Acinetobacter baumannii burden in a mouse skin-abscess model, with efficacy comparable to polymyxin B.
More broadly, the work argues that open, standardized biological data can make it easier for machines to help scientists understand and engineer biology, and speed up discovery in human health.
Related event: AllTheBacteria Standardizes 2.44M Genomes for AI, Finding New Antibiotics(3 posts)→
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