BioEmu: Predicting Protein Conformational Changes
FrankNoeBerlin · x · 2026-07-18
BioEmu acts as a protein structure "simulator": input a protein sequence, and it outputs a **3D structure distribution** rather than a single structure. It aims to simulate the **构象变化** and **热力学概率** of real proteins, meaning it can not only predict multiple conformations but also estimate their relative probabilities. The post mentioned that the author presented this at the Mayo Clinic's biochemistry department, outlining the next steps for this research direction following AlphaFold.
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