ATHENA Masters 212 Biomedical Tools via Two-Stage Self-Learning

marinkazitnik · x · 2026-07-07

ATHENA is capable of identifying missing information and invoking the correct tools at each reasoning step, covering 212 biomedical tools to ultimately form an inspectable, complete reasoning chain. Because manual annotation at this scale is infeasible, training was divided into two stages: the first stage involved agents autonomously generating tool-calling trajectories for supervised fine-tuning; the second stage utilized reinforcement learning with scientific feedback rewards to further optimize the policy, enabling large-scale training without human annotation.

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