Two Major Cardiovascular Trials Fail, AI Offers Clues

Two large cardiovascular prevention trials reported simultaneously at AHA26 and in NEJM—an IL-6 antibody and an Lp(a) antisense oligonucleotide—showed no benefit. Cardiologist Eric Topol used AI-based coronary inflammation quantification to explain the failures, while other experts pushed back on hopes of AI curing disease within five years.

2026-11-08 ~ 2026-11-09 · 2 related posts

• AI-quantified coronary inflammation explains why two major cardio trials failed, Topol says — EricTopol · 2026-11-08
• Two major cardiology trials fail, a reality check for 'AI will cure all disease' — anshulkundaje · 2026-11-09