ProteinMPNN May Memorize Transmembrane Folds; Noise Disables Recognition

Researcher sokrypton hypothesizes that ProteinMPNN memorized which folds are transmembrane, explaining why it needed retraining; adding noise at around 0.3 level disrupts this recognition.

2026-11-05 ~ 2026-11-05 · 2 related posts

• ProteinMPNN likely memorized transmembrane folds; 0.3 noise breaks the recognition — sokrypton · 2026-11-05
• ProteinMPNN memorizes transmembrane folds: noise may trick it, devs speculate — sokrypton · 2026-11-05