ipSAE Scoring Extended to Ligands and Protein-Nucleic Acid Complexes

Roland Dunbrack's new bioRxiv preprint extends the ipSAE score from protein-protein complexes to protein-ligand and protein-nucleic acid complexes, fixing ipTM distortion issues in AlphaFold3 and Boltz-2 predictions.

2026-11-04 ~ 2026-11-05 · 2 related posts

• bioRxiv preprint extends ipSAE confidence scoring to diverse molecular complexes — victorgreiff · 2026-11-04
• ipSAE extends to ligands: fixing poor ipTM scoring in AF3 and Boltz-2 cofolding models — sokrypton · 2026-11-05