Preprint Quantifies Data Leakage: Near-0.8 AUC With No Signal

A new preprint co-authored with Jake Vogel shows data leakage is a common reason proteomics biomarker studies fail to replicate: even with no true signal, leaked models can achieve an AUC near 0.8.

2026-09-11 ~ 2026-09-11 · 2 related posts