Developer Creates Protein Font by Backpropagating Through ESMFold

Inspired by an Anthropic post, developer @alexpeys used reverse differentiation through the ESMFold2 protein folding model to design proteins whose folded distance maps form letters, creating a "protein font" with help from Codex, though manual adjustments were still required.

2026-08-19 ~ 2026-08-19 · 2 related posts

• Developer creates protein font using ESMFold and reverse differentiation — alex_peys · 2026-08-19
• Designer builds a protein font: 26 proteins that fold into letters via ESM-Fold2 backprop — alex_peys · 2026-08-19